Empore™ Filter Aid 400 and/or prefiltration may be helpful if the sample contains excessive particulates. If the sample contains a high concentration of suspended solids, allow the particles to settle (overnight if necessary). Tilting the sample container to allow particulates to settle on one side is suggested to aid in decanting only the liquid portion of the sample. Particulates can be added to the reservoir after most of the sample has been processed. The 90 mm disk is recommended for samples with excessive particulates or to reduce sample processing times.
Empore SPE disks are high density (HD) membranes composed of chromatographic particles averaging 10-12 μm in size. The high density membranes are designed for maximum extraction efficiency with minimal elution volumes for samples that have less matrix interference.
Empore™ Disk Technology
Empore™ Solid Phase Extraction Disks are produced by trapping sorbent particles within an inert matrix of polytetrafluoroethylene (PTFE). The resulting particle-loaded membrane yields a denser, more uniform extraction bed than can be achieved with traditional loosely packed SPE particles. The result is improved mass transfer kinetics with consistent performance in solid phase extraction methods.
The dense particle packing and uniform distribution within Empore disks offer outstanding sample preparation efficiency and reproducibility of results. Since the diffusion distance between particles is minimized, adsorption is more efficient, and extraction can be accomplished using low sorbent mass. The following performance gains can be realized:
• Reduced solvent volumes
• Small elution volumes
• Reduced time for eluate evaporation
• High throughput
• Channeling effects eliminated
• Excellent reproducibility/low CVs