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PathHunter® Activated GPCR Endocytosis Assays  

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PathHunter® Activated GPCR Internalization Assays provide a quantitative measurement of internalized GPCR protein localized to the endocytic compartment and let you monitor the cellular...
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PathHunter® Total GPCR Endocytosis Assay  

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PathHunter® Total GPCR Endocytosis Assay provides a quantitative measurement of total GPCR protein whether it is localized to the cell surface or internalized into endosomes. In this...
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PathHunter™ ß-arrestin Assays  

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PathHunter™ ß-arrestin Assays are revolutionary high-throughput screening assays for monitoring G-protein coupled receptor (GPCR) activation following ligand stimulation, without an imaging...
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PathHunter™ EAstern Blot Assay Kit  

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Fast Antibody-free Alternative to Western Blot The PathHunter™ EAstern Blot Assay Kit offers a new antibody-free method for recombinant protein characterization based on ß-galactosidase...
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PathHunter™ Cell Cycle Assays  

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Overview & Description PathHunter™ Mitotic Index Assays are novel biosensor cell assays that uniquely meet the need for easy, cost-effective HTS assays to identify compounds or...
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ADP Hunter Plus and ADP Quest Kinase Assays  

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ADP Hunter and ADP Quest assays from DiscoveRx are generic, homogeneous, antibody-free, non-radioactive kinase assays that measure ADP accumulation.  ADP Quest™  and ADP Quest HS...
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ADP Hunter™ HS - High Sensivity Kinase Assay  

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ADP Hunter™ HS assay is a unique tool for screening kinases and extends the range of ADP detection down to 300 nM ADP without compromising Z'. The assay employs a generic, non-antibody...
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Calcium No Wash Assay Kit  

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Overview and Description The DiscoveRx Calcium No Wash (Ca NW) Assay kit provides a fast, reliable, low cost alternative to traditional wash and quench-based assays for detection of...
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Coelenterazine h  

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Overview Aequorin is a calcium-sensitive bioluminescent protein from the jellyfish Aequorea victoria that has been used extensively as a calcium indicator in cells. The aequorin complex...
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Custom EFC Assays  

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We'll build assay that you need!! DiscoveRx is an innovative company with technology that has been applied successfully in a very broad range of target areas in discovery research,...
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Custom EFC Services  

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We'll Build EFC Assay Tools to Meet Your Needs Our innovative technology has been successfully applied to many target areas in discovery research, including oncology, metabolic disease,...
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HitHunter cAMP Assay Kits  

4 out of 5

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Overview and Description HitHunter cAMP Assays are applicable for cell based screening of G-protein coupled GPCR activation in a homogeneous, non-radioactive microtiter plate format.
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  • Ease of use 5 out of 5
  • After sales service 3 out of 5
  • Value for money 3 out of 5

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HitHunter™ cGMP Assay  

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Overview and Description Guanosine 3’5’-cyclic monophosphate (cGMP) is an intracellular second messenger. Either receptor bound natriuretic peptides or nitrous oxide activate the...
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HitHunter™ Cortisol Assay  

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Cortisol is a steroid hormone that is produced and secreted by adrenal cortex. As the major glucocorticoid in the human body, it is involved in stress adaptation, blood pressure elevation...
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HitHunter™ EFC Kinase Assays  

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Overview & Description Kinase enzymes are known to have broad substrate specificity and can phosphorylate a number of non-physiological substrates in vitro. When evaluating kinase...
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HitHunter™ FP Kinase Assays  

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Overview and Description Kinase enzymes are known to have broad substrate specificity and can phosphorylate a number of non-physiological substrates in vitro. When evaluating kinase...
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HitHunter™ IP3 FP Assay  

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Overview & Description Ligand binding of Gq-protein coupled receptors on the cell surface activate phopholipase C (PLC) to produce two critical second messengers – Diacylglycerol (DAG)...
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HitHunter™ Kinase Binding Assays for Unactive Kinases  

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Description and Overview When little or no information is known about the kinase substrate and its associated antibody, an alternative approach is inhibitor binding directly or...
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HitHunter™ Nuclear Hormone Assays  

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Nuclear receptors (NRs) are a superfamily of ligand-dependent transcription factors that control diverse aspects of growth, development and homeostasis, making them exciting and important...
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HitHunter™ Protease Assays  

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There are about 475 known putative proteases in the human genome. Proteases participate in a wide variety of physiological processes by controlling complex proteolytic cascades. Many...
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InCELL Hunter  

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DiscoveRx has developed a simple and powerful in vivo cellular ligand binding assays to determine compound binding in a native cellular environment. Our InCELL Hunter™ platform uses the EFC...
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Ion Channel Cell Line - hERG  

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Overview Mutations in the human ether-a-go-go-related gene product (hERG) potassium channel have been associated with the potentially lethal inherited long QT syndrome (LQT).
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KINOMEscan™ Binding Assays  

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The KINOMEscan screening platform employs a novel and proprietary active site-directed competition binding assay to quantitatively measure interactions between test compounds and more...
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PathHunter™ Flash Detection Kit  

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High-throughput-ß-arrestin Assays: Now with 30-second Detection With the PathHunter™ Flash Detection Kit, ß-arrestin recruitment by a GPCR can now be detected in 30 seconds¡--permitting...
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PathHunter™ GPCR Explorer Kit  

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The PathHunter™ GPCR Explorer Kit, a fast and simple system that enables development of novel GPCR biosensor assays for any GPCR in just 3 days. Whether you have a panel of mutant GPCR...
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