Phosphorylation Site Specific Aptamers for Cancer Biomarker Peptide Enrichment and Detection in Mass Spectrometry Based Proteomics
22 April 2015
The development of renewable capture reagents that could be produced more efficiently and cost-effectively than monoclonal antibodies is a key topic in diagnostics and therapeutics. The cancer research community has demonstrated a critical need for these reagents for biomarker detection. Base Pair Biotechnologies has developed high-affinity aptamers against specific phosphorylated and unmodified peptide target sequences of certain cancer biomarkers of interest.