New Tools for Drug Discovery: Multiplexing the Monitoring of Ca2+ and cAMP Signaling in Primary Cells Using the FDSS®/µCELL
27 Jan 2015

This application note demonstrates the suitability of primary cells for signaling assays in compound screenings using primary and stem cells expressing luminescent biosensor proteins specific for Ca2+ and cAMP. These assay formats are used on the FDSS®/µCELL plate reader to generate pharmacologically relevant data for GPCR ligands.

Show    per page
1 of 11     Page  1 2 3  ... Next 
A Fluorogenic Assay for Identification of Coagulation Factor IIa Inhibitors automation22 Jan 2015Read
Analytical Sensitivity of Samples Tested with the Crocodile miniWorkstation in Comparison to Hand Processing Using PrioCHECK® Toxoplasma Ab porcine ELISA from Prionics AG toxicity22 Jan 2015Read
Monitoring Intracellular Ca2+ Fluxes with Clonetics™ Primary Sensors using the Orion II Microplate Luminometer calcium20 Jan 2015Read
Miniaturization of a Cell-based TNF-α AlphaLISA® Assay Using Echo® Liquid Handler and the PHERAstar FS inflammatory diseases19 Jan 2015Read
Fluorescence-Based DNA Quantification in Low Volumes Using the Infinite® M1000 and Infinite F500 Multimode Readers DNA quantification16 Jan 2015Read
Fast Quantification of Saliva Samples in Microplates Using Tecan’s Infinite® F50 ELISA Reader automation13 Jan 2015Read
ABEL® Cell Activation Assay for Whole Blood or Isolated Cells with Pholasin® and Adjuvant-K™ blood analysis13 Jan 2015Read
Using CLARIOstar® Fluorescence Polarization Detection to Perform hERG Predictor™ Assay cardiotoxicity12 Jan 2015Read
Looking for a Strong Promoter for Physcomitrella patens plant science12 Jan 2015Read
Profiling Receptor Tyrosine Kinase Activity with Corning® Epic® Label-Free Technology receptors, Kinases8 Jan 2015Read

Popular tags in SelectScience