Application of an Improved High-Throughput Lipid Extraction Method for the Analysis of Changes in Brain Lipid Species in Parkinson's Disease
25 Nov 2014

Traditional lipid extraction techniques are the bottleneck for modern shotgun lipidomic studies. To overcome this problem, protocol comparisons were made between the well-established Folch extraction (using glass-glass homogenization) and a modified method that employed mechanical homogenization (Precellys-24, Bertin Technologies) and replaced chloroform with MTBE. This significantly reduced sample handling time and increased efficiency compared to glass-glass homogenizing.

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Comprehensive Characterization of Trastuzumab using a Single-Shot Peptide Mapping Approach with CESI-MS monoclonal antibodies, peptide mapping25 Nov 2014Read
Simultaneous Quantitative Peptide Mapping and Host Cell Protein Detection in a Recombinant IgG1 Monoclonal Antibody Preparation using Data-Independent Acquisition monoclonal antibodies, biotherapeutics, Mass Spectrometry21 Nov 2014Read
A Validated Assay for the Quantification of Amino Acids in Mammalian Urine amino acids, urine analysis, human urine19 Nov 2014Read
Evaluating the Integration of CE, ESI and Mass Spectrometry for the Quantitative Analysis of Amino Acids in the Cationic Metabolome amino acids, metabolomics18 Nov 2014Read
A Robust and Sensitive Automated Method for Mass Spectrometry-Based Serum Pattern Diagnostics Using Well-Established ZipTip Technology high throughput, peptides, Mass Spectrometry17 Nov 2014Read
Top-Down and Bottom-Up Proteomics with the Agilent 1290 Infinity 2D-LC Solution Using DAD and Q-TOF LC/MS protein analysis, proteomics, 2D chromatography14 Nov 2014Read
Solutions for Mass Spectrometric Detection from Merck Millipore method development, Mass Spectrometry6 Nov 2014Read
A Label-Free, Multi-Omic Study to Qualitatively and Quantitatively Characterize the Effects of a Glucosylceramide Inhibitor on Obesity chromatography method development4 Nov 2014Read
Understanding Sample Complexity and Improving Quantitative Data Quality Using RADAR™ method development, Mass Spectrometry27 Oct 2014Read
The XS Collision Cell from Waters Offers Increased Sensitivity and Resolution for Time-of-Flight Mass Spectrometry Mass Spectrometry27 Oct 2014Read

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