Unique Software Tools to Enable Quick Screening and Identification of Drugs of Abuse and Metabolites in Forensic Samples using Accurate Mass LC-MS/MS
7 May 2013
In this application note high resolution and accurate mass LC-MS/MS was used to screen for and identify drugs of abuse and metabolites in equine urine samples. The AB SCIEX TripleTOF® system was operated in IDA mode to acquire MS and MS/MS information simultaneously. The XIC Manager add-in of PeakView® software was used for screening and identification with highest confidence by automatically processing LC-MS/MS data using information on retention times, accurate mass, isotopic pattern and MS/MS library searching. This data processing workflow enables high throughput data analysis.
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