Applying Transfection Technologies to Create Novel Screening Models
19 June 2013
The availability of human induced pluripotent stem cell (iPSC)-derived cells offers new opportunities for the generation of novel, physiologically relevant cellular models for drug screening and development. Realizing the full potential of these cellular models requires molecular techniques that enable introduction of exogenous genes and/or modulation of endogenous genetic elements. In this application note read how various types of iPSCs are compatible with transfection reagents to deliver, plasmid DNA, siRNA and reporter gene constructs. This enables investigation of specific target genes for numerous applications in drug discovery research.
