Quantitation and Identification of Pharmaceuticals and Personal Care Products (PPCP) in Environmental Samples using Advanced TripleTOF MS/MS Technology
30 Jul 2014
Liquid Chromatography coupled to tandem Mass Spectrometry (LC-MS/MS) is a preferred tool for the analysis of a wide range of environmental pollutants. Here, a method is presented using the AB SCIEX TripleTOF® 4600 LC/MS/MS system to identify and quantify selected PPCP in water samples. Different scan functions are applied and compared with respect to selectivity, sensitivity, accuracy, reproducibility, and confidence of identification. Data was processed in MultiQuant™ and PeakView® software using a new mass spectral library containing high resolution and accurate mass MS/MS spectra acquired on a TripleTOF® system.