Detection of Small Molecules on a Pyrrole-Streptavidin Biochip
2 May 2016
This application note demonstrates that the SPRi-Biochip™ is capable of detecting molecules with molecular weights as low as 244 Da. The biological interaction chosen for this experiment is the streptavidin / biotin model. Streptavidin conjugated to a pyrrole molecule is electro-copolymerized on the gold surface of a bio-chip. The biotin is then captured on the biochip due to the strong streptavidin-biotin affinity.