Improve Your Laboratory's Analytical Power with ACQUITY UPC2

3 Mar 2013
Laura Burnett
cfcfcgfc

UltraPerformance Convergence Chromatography™ [UPC2™] is a modernization of supercritical fluid chromatography [SFC] technology holistically designed to deliver reliability, robustness, sensitivity and throughput never before possible for this analytical technique.

Attend a free educational seminar at Pittcon 2013: UltraPerformance Convergence Chromatography: Expanding Selectivity for the Chromatographic Laboratory


UltraPerformance Convergence Chromatography [UPC2] utilizes liquid CO2 as a mobile phase to leverage the chromatographic principles and selectivity of normal-phase chromatography while providing the ease-of-use of reversed-phase LC. Unlike normal-phase LC, supercritical CO2 is miscible with the entire eluotropic series of solvents. In addition, traditional normal-phase and reversed-phase column chemistries can both be utilized. This ability to combine a wide range of column and solvent choices allows chromatographers to develop separations covering a very diverse range of compounds and application areas. In this seminar, we will discuss this exceptional increase in available selectivity that convergence chromatography brings to the laboratory.

Find out more of what convergence chromatographycan do for your laboratory.

ACQUITY UPC² System

Waters

Convergence Chromatography with the ACQUITY UPC² System Bring streamlined workflow, expanded selectivity, and an orthogonal technique to your laboratory. Convergence chromatography (CC) is a broad-based, complementary analytical platform that is taking its place alongside of LC and GC as one of the three essential separation technologies for modern laboratory analysis. This technique provides another, reliable choice as an analytical platform that is orthogonal to reversed-phase LC (RPLC), while significantly streamlining the entire analytical workflow. In convergence chromatography, the separation is achieved by manipulating the density and composition of a supercritical fluid-based mobile phase. Because of the very high diffusivity of the mobile phase, can be achieved. Additionally, the diversity of stationary phase and mobile phase (co-solvent) options provides access to the largest selectivity space available to any separation technique. The ACQUITY UPC² System is a holistically designed UltraPerformance Convergence Chromatography (UPC²) system that utilizes liquid CO2 as the primary mobile phase. The system leverages the chromatographic principles and selectivity of normal-phase chromatography while providing the ease-of-use of RPLC, enabling you to address routine and complex separations challenges. ACQUITY UPC² System: Discover what's been missing from your analytical toolbox With the ACQUITY UPC² System, scientists can now separate, analyze, and understand compounds that have challenged all other LC and GC technologies including: Hydrophobic and chiral compounds Lipids Thermally-labile samples Polymers It's also the perfect complement to MS due to its low solvent load and high resolution, narrow peaks and fast separations. ACQUITY UPC² System Features: Compressed carbon dioxide (CO2), the primary mobile phase, is less costly and less toxic than liquid mobile phases or carrier gases. Variable volume injection delivers 0.5 µL to 10 µL as well as the ability to match column and injection volume with minimal sample loss and need to change loops. Higher throughput and productivity allows you to analyze more samples per day with faster re-equilibration of columns and shorter cycle times, increasing laboratory productivity. Co-solvent and column switching provides flexibility in method development for faster solvent screening and faster column screening.

(18)

Links

Tags

Improve Your Laboratory's Analytical Power with ACQUITY UPC2