Stable Isotope-Labeled ApoA-I as a Global Standard for Quantitative Proteomic Studies
5 October 2016
Cardiovascular disease (CVD) is the number one cause of morbidity and mortality worldwide. However, reliable diagnostic tests of CVD risk are lacking. To accurately quantify proteins using mass spectrometry, as required in a clinical setting, the variability of all steps of an analytical process must be controlled. Read this application note to learn more about a novel SRM-based approach, with 15N-labeled human ApoA-I serving as the internal protein standard.