Application of the Bioruptor® Pico for shearing chromatin fragments for ChIP-seq from human tumor tissue
19 June 2015

This application note illustrates how the Bioruptor® Pico (Diagenode) can process various human tumor tissues for ChIP-seq analyses of transcription factors as well as epigenetic marks.  Chromatin must be optimally sheared prior to immunoprecipitation and subsequent library preparation for Illumina sequencing.