HPLC Analysis of Acetaminophen Tablets with Waters Alliance and Agilent Supplies
25 August 2015

Acetaminophen, also known as paracetamol, is a common pharmaceutical widely used to relieve pain and reduce fever. This application note validates a method to analyze paracetamol tablets, demonstrates the performance maintenance of a number of Agilent consumables, and assesses the compatibility with a Waters Alliance system. Detection limits, linearity, accuracy and precision, and sample recovery were determined. These parameters are important indicators of the functionality of the system, the column, and sample preparation (filtration) products.