Application Note: Applicability of Function Tested RealTime ready Assays for Gene Expression Analysis in Biomarker Research and Early Drug Development
27 June 2013
Personalized health care (PHC) uses gene-based information to understand requirements for health maintenance, disease prevention, and therapy, all tailored to an individual’s genetic uniqueness. The identification and characterization of molecular biomarkers, used as indicators for a certain biological state, plays an important role in personalized healthcare. Biomarkers are therefore a central element in a drug’s lifecycle, from target identification to drug application.
Prostate-specific antigen (PSA), c-reactive protein (CRP), and HER2/neu are just a few examples of molecular biomarkers. In biomarker research, the investigation of mRNA expression profiles in the context of complex biological pathways is of great interest. Download this application note to read how RealTime ready RT-qPCR assays can be successfully applied in biomarker research using both in vivo and in vitro models and FFPE tissues.