Application Note: DNA Extraction From Hair Using Pressure Cycling Technology (PCT)
31 July 2012
Current methods for extracting DNA from hair shafts involve extensive sample preparation and
processing, and often require the use of hazardous chemicals. Even though most hair extraction
methods include a post extraction clean-up or concentration step, PCR inhibitors may still be present
and interfere with downstream sample processing and analyses. A technology novel to the forensic
community, i.e., pressure cycling, has the potential to enhance current DNA extraction methods by
increasing DNA recovery while preserving the quality of the DNA.