Application Note: Screening HDAC Inhibitors – A Workflow Comprising High Throughput and High Content Screening
9 August 2013

To allow efficient screening of large compound libraries, intelligent screening workflows are needed that combine different assay formats and multiplex various readouts, including phenotypic information, to provide a more holistic view of compound effects. This application note demonstrates the potential power of combinatorial screening campaigns. An AlphaLISA assay was run on the EnVision Multilabel Plate Reader as a primary screen and a number of active compounds were then selected to be further analyzed and verified in a cellular assay using the Operetta High Content Imaging System.

Download PDF >>PDF Icon

Read the full article...

  Become a member
  • Quick and complete access to all application articles

  • Download 10,000+
    applications and methods

  • Make informed buying decisions

Already a member?

Log in for full access to the article

Remember me