A Novel, Substrate-Agnostic Class III HDAC Activity Assay
13 August 2012

Read this note featuring an application for epigenetics research. An assay platform that enables the analysis of sirtuin activity using virtually any appropriate substrate has been developed and is outlinesd here. This new SIRTainty™ class III HDAC assay is a flexible, reliable, homogeneous, no-wash assay for quantifying sirtuin activity. Based upon novel, patent-pending technology, this easy-to-perform assay is coupled to nicotinamidase, which catalyzes breakdown of nicotinamide generated upon cleavage of NAD+ during sirtuin-mediated deacetylation of a substrate.

Popular tags in SelectScience

Buying guides

Write a Review

Join the Global SelectScience Community Today! It’s FREE!

Helping you make informed decisions about the latest lab products and technologies:

  • Be the first to learn about new technologies
  • 10,000+ trusted product reviews from your peers
  • Compare 500,000 products and manufacturers
  • Get exclusive buying tips from experts
  • Find solutions fast: 10,000+ Application Notes, Webinars and Videos

Connect with 250,000 scientists... All in one place!

Become a member today!