ResourceLife Sciences
Cytogenetic Monitoring of Cancer Progression in Circulating Tumor Cells Utilizing the IsoFlux System and GenASIs Spectral Imaging Technology
30 Apr 2013Fluorescence in situ hybridization (FISH) has emerged as a clinically-useful tool for understanding patient-specific traits of cancer at the molecular level. FISH is typically performed on biopsied tissue samples obtained during surgery. Circulating tumor cells (CTCs) have emerged as a potential source of clinically-useful information that can be accessed with far greater frequency than tissue biopsies. In addition to discussing the current challenges for running FISH on CTCs, this application note presents a complete method for CTC analysis.
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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.ElectrophysiologyElectrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.FISHCTCsCancer CellsCancer cells are abnormal cells that divide uncontrollably, leading to the formation of tumors and the spread of cancer. Studying cancer cells is crucial for developing new treatments and understanding tumor biology. Explore cancer cell research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.