Oncology: Melanoma – Metastasis
30 Apr 2013Melanoma is the most aggressive form of skin cancer, which invades deeper layers of the skin and has a propensity to metastasize early. In an effort to provide insight into the mechanism by which melanoma cells metastasize, this application note examines differential cell adhesion within an isogenic model of melanoma progression under physiological shear flow conditions using the Cellix VenaFlux™ Platform.
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Vena8 Endothelial+ Biochip: microfluidic flow chamber
Cellix LtdThe Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging and fluorescence imaging to study cell-cell interactions under conditions mimicking physiological flow.