Cardiovascular: Atherosclerosis - Monocyte Adhesion - Chemokines -Oxidized LDL

28 Apr 2013

This application note investigates the role of different stimuli recognized to play an important part in atherosclerosis development (chemokines, cytokines, oxidized lipoproteins) on leukocyte adhesion to endothelial cells or purified adhesion molecules, under physiological flow conditions using Cellix’s VenaFlux™ platform and biochips.

Vena8 Endothelial+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging and fluorescence imaging to study cell-cell interactions under conditions mimicking physiological flow.

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Cardiovascular: Atherosclerosis - Monocyte Adhesion - Chemokines -Oxidized LDL