Multiplexed Assay for IL-6 Secretion and Cell Viability using an Epithelial Ovarian Cancer Cell Line
7 Apr 2014

Approximately 90% of diagnosed ovarian cancers are classified as “epithelial”. A common manifestation of EOC at this late stage of its progression is a build-up of fluid in the abdominal cavity (ascites). It has been shown that high levels of IL-6 are present in patients with ascites. In this application note, the authors demonstrate an in vitro microplate assay that can monitor IL-6 secretion from plated SKOV-3 ovarian carcinoma cells induced through EGFR ligand binding and NFkB activation.

Show    per page
1 of 4     Page  1 2 3  ... Next 
Perfecta3D® Hanging Drop Plates Case Study: Huntington Medical Research Institutes (HMRI) 3d cell culture, tumor, AACR10 Apr 2014Read
Plant Metabolomics Research Highlight: Prof. Lloyd W. Sumner Combines UHPLC-MS-SPE-NMR and Prof. Kazuki Saito Employs FT-ICR-MS in Novel Strategies to Identify Unknown Plant Metabolites metabolomics, plant science6 May 2014Read
Research Using Rapid Assessment of AML Genes for Mutation Detection leukemia, cancer, copy number variation10 Apr 2014Read
Toxtyper™ – a Comprehensive LC-MSn application for Clinical Research and Forensic Toxicology drugs of abuse, clinical study, forensic toxicology7 May 2014Read
LC-MS/MS Analysis in Immunosuppressant Drug Research using EVOQ™ Elite LC-MS/MS System pharmacokinetics, pharmaceuticals7 May 2014Read
MALDI Imaging Success Stories in Clinical Research clinical study, pharmaceuticals8 May 2014Read
Using iPSC-Derived Hepatocytes as a Functional Model System for Human Hepatitis Research hepatitis, liver disease, Hepatocytes28 Oct 2013Read
Use of the Contichrom® Platform in Discovery and Life Science Research chromatography method development, chromatography, drug discovery4 Dec 2013Read
Quantitative Analysis of Dried Bloodspot 17-Hydroxyprogesterone by ACQUITY UPLC-MS/MS for Clinical Research blood spot, steroids12 Jun 2014Read
A Rapid and Analytically Sensitive LC-MS Method for the Simultaneous Analysis of a Panel of Steroid Hormones for Clinical Research hormones, solid phase extraction, steroids22 Sep 2014Read

Popular tags in SelectScience