White Paper: When to Use Targeted Resequencing — Choosing the Right NGS Method
17 July 2013
With such proliferation of next generation sequencing (NGS) technologies and methods, it may not always be immediately obvious which approach is the most suitable for a given study. While whole genome sequencing (WGS) provides the most comprehensive data, it is not a cost-effective technique for identifying rare variants such as those found in heterogeneous cancer samples. It also generates high volumes of data, which makes analysis particularly complex and resource-intensive. This whitepaper aims to examine the various targeted resequencing strategies available and explore when they are appropriate, in order to aid investigators in choosing the most suitable NGS method.
