High Throughput, Quantitative Ligand Binding Assays for Human Bromodomains
7 Mar 2012

This poster describes a robust screening platform designed to identify small molecule inhibitors of bromodomain-containing proteins. These are a large family of epigenetic 'reader-proteins', which have been associated with disease and represent an important new druggable target class. Using, DiscoveRx Corporation's KINOMEscan binding assay technology, a comprehensive panel has been developed, suitable for high throughput screening.

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