Application Note: Disulfide Bridge Mapping by LC MS/MS
9 November 2012

Understanding protein structures is essential to the development of protein-based therapeutics since the 3D structure of a protein is directly related to its efficacy. This application note from Protea Biosciences highlights the utility of high resolution mass spectrometry analysis and the latest bioinformatics software in mapping disulfides in two common proteins, lysozyme and BSA.