Application Note: Direct Determination of Small Organic Acids in Sea Water by IC-MS
3 October 2012

In this application note from Thermo Fisher Scientific a 2D-IC-MS system that allows low levels of small organic acids (C1-5) to be analyzed in a high-ionic-strength matrix is described. The first dimension of the system separates the low-level analytes from the matrix while the second resolves each of the target analytes. The mass spectrometer confirms identity and achieves low detection limits for a sensitive and selective assay.