Biomarker Quantitation in Human Plasma by Multiple Reaction Monitoring (MRM)
17 December 2012

In this application note an effective tool for the absolute quantitation of targeted protein by mass spectrometry based multiple reaction monitoring (MRM) is described. In this investigation, nine signature peptides were used for quantitation of the original seven proteins fortified into female human plasma. The accuracy, precision, sensitivity, and linearity of targeted protein quantitation by MRM were evaluated. Two human proteins and five from other species previously detected at low levels were confidently quantified. The results explain why MRM is quickly becoming the standard for protein biomarker verification.

Popular tags in SelectScience

Buying guides

Write a Review

Join the Global SelectScience Community Today! It’s FREE!

Helping you make informed decisions about the latest lab products and technologies:

  • Be the first to learn about new technologies
  • 10,000+ trusted product reviews from your peers
  • Compare 500,000 products and manufacturers
  • Get exclusive buying tips from experts
  • Find solutions fast: 10,000+ Application Notes, Webinars and Videos

Connect with 250,000 scientists... All in one place!

Become a member today!