Application Note: Automated High Throughput Functional Cell-based Bioassays for EGFR Blocking Antibodies
11 July 2012

In this study, a novel, target-specific cell-based assay platform that can be used to detect and differentiate potential inhibitors of Epidermal Growth Factor receptors is described. The assay uses a full-length receptor protein and is based on a proprietary Enzyme Fragment Complementation (EFC) Assay Technology in a whole cell platform enabling antibody interrogation and characterization in a cellular context. The assay was automated in 384-well format, making it ideal for screening antibody clones.

Download PDF >>PDF Icon

Read the full article...

  Become a member
  • Quick and complete access to all application articles

  • Download 10,000+
    applications and methods

  • Make informed buying decisions

Already a member?

Log in for full access to the article

Remember me