Application Note: Analysis of PEG and a PEGylated Therapeutic Protein Using an Agilent HPLC-Chip Coupled to a Q-TOF Mass Spectrometer
11 September 2015

This application note describes the development of a method to analyze PEG and PEGylated protein using an Agilent 1260 Infinity HPLC-Chip coupled to an Agilent 6520 Accurate-Mass Q-TOF LC/MS System. The results show improvement in the mass spectrum quality for PEG and the PEGylated protein.