Application Note: Analysis of Monoclonal Antibody Charge Variants by Capillary Zone Electrophoresis
20 March 2013

This application note compares two methods for separating monoclonal antibody charge variants; capillary isoelectric focusing (cIEF) and capillary zone electrophoresis (CZE). Results show that CZE is capable of providing faster, highly reproducible separations for a representative monoclonal antibody, highlighting this method as a faster alternative to cIEF.

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