Developability Assessment Using the HUNK
13 October 2016
The HUNK, a fully automated chemical denaturation system, provides and effective means to assess the stability of proteins. This application note describes how the HUNK can be used as a predictive tool to assess protein conformational stability, amount of denatured protein, and the mode and propensity for aggregation. This information can guide decisions on protein construct design and reduce the risk of downstream formulation challenges.