Antibodies Laboratory Application Articles and Antibodies Scientific Posters on SelectScience

Advantages of Online 2D Chromatography for MRM Quantification of Therapeutic Monoclonal Antibodies in Serum
14 May 2013

In this application note, it is demonstrated that a two-dimensional chromatographic assay (2D LC or 2D UPLC) for multiple reaction monitoring (MRM) quantification in protein bioanalysis can provide up to a three-fold increase in sensitivity compared to one-dimensional LC/MRM. Additionally, high pH/low pH RP/RP separations can significantly reduce analyte suppression.

Download this article

Show per page

1 of 4 Page 1 2 3 ... Next

Characterization of Antibodies and Antibody Drug Conjugates by a Novel High Resolution Quadrupole Time-of-Flight Mass Spectrometer	monoclonal antibodies, conjugation, antibody drug conjugates	8 May 2013	Read
A Modular Approach for Epitope Discovery and High-Resolution Profiling of Humoral Immune Responses	companion diagnostics, peptides, epitope	3 May 2013	Read
Characterization of the N-glycosylation Pattern of Antibodies by ESI - and MALDI Mass Spectrometry	biopharmaceuticals, glycosylation, glycoprotein	22 Apr 2013	Read
Biodistribution Monitoring Using the iBox Explorer2 Imaging Microscope	fluorescence, cancer, small animal imaging	5 Apr 2013	Read
Method Development for Size-Exclusion Chromatography of Monoclonal Antibodies and Higher Order Aggregates	monoclonal antibodies, aggregation, protein analysis	2 Apr 2013	Read
Comparison of AF4, AUC and SEC for Monoclonal Antibody Aggregate Quantitation	monoclonal antibodies, biopharmaceuticals, biopharmaceutical manufacturing	21 Mar 2013	Read
Homogeneous Binding Assay for High Throughput Antibody Screening	high throughput, antibody arrays, screening	20 Mar 2013	Read
A Mix-and-Read Cell-Based Assay for Antibody Screening Against Epidermal Growth Factor Receptor	multiplex, antibody arrays, screening	20 Mar 2013	Read
Analysis of Monoclonal Antibody Charge Variants by Capillary Zone Electrophoresis	quality control, Antibody production	20 Mar 2013	Read
Homogeneous Binding Assay for Hybridoma Screening: Comparison of Laser Scanning Systems	monoclonal antibodies, antibody arrays, therapeutics	12 Mar 2013	Read