Metoprolol and Select Impurities Analysis
30 June 2015

This application note demonstrates a technique for the impurity profiling of the drug metoprolol succinate USP. This technique produces consistent analyte response independent of chemical characteristics and gives greater sensitivity over a wider dynamic range than ELSD. The presence of chromophoric groups, radiolabels, ionizable moieties, or chemical derivatization is not needed for detection.