Middle-Down Analysis of Monoclonal Antibody Using Nano-Flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer
21 Jan 2015

This application note demonstrates sensitive analysis of monoclonal antibody using a middle-down approach on a novel Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer. The method combines nano-flow liquid chromatography and complementary higher-energy collisional dissociation (HCD) and electron transfer dissociation (ETD) fragmentation on an Orbitrap Fusion Mass Spectrometer.

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Middle-Down Analysis of Monoclonal Antibody Middle Using Nano-flow Liquid Chromatography and a Novel Tribrid Orbitrap Mass Spectrometer monoclonal antibodies, protein analysis, glycosylation13 Jan 2015Read
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