Standardizing the Quality Control of Any DNA Isolation to Safeguard the Success of Genetic Testing
7 December 2015
This application note validates a novel approach for DNA quality assessment using a large DNA sample set derived from a variety of human tissues combined with a wide scale of extraction methods. Genetic tests become ever more powerful, yet also more complex and costly, which is why it is prudent to include quality control steps throughout the preparation process to ensure the quality of the downstream data obtained. To make an informed go/no go decision and avoid analytical failures, a good assessment of the yield and purity of DNA/RNA isolations is essential, including the detection of carry-over constituents that may interfere with downstream tests.