How to Buy Liquid Handling Technology
15 September 2016

Introduction

Precise and accurate delivery of samples and reagents is fundamental for many sensitive techniques employed in today’s laboratories. Liquid handling devices draw in (aspirate) a given volume of liquid from a source container and deliver (dispense) this liquid to the destination container once it has been appropriately re-positioned. The fluid being transferred, often referred to as the sample fluid, is frequently held in tips. These tips can either be permanent features of the liquid handler or disposable pieces.

Advancements in technology have resulted in the evolution of liquid transfer solutions, from the dispensing of sample fluid from an individual tip to large-scale automated liquid handling involving many tips, channels, robots and large workstations. Aspiration and dispensing of sample fluid is typically carried out in the microliter, milliliter and nanoliter range. However, it is now also possible to dispense volumes in the picoliter range, and femtoliter dispensing may be possible for microarray applications in the future.

 

Table 1: Technique Optimizations of Liquid Handling Technology

Industry

Techniques

Pharmaceutical – Discovery & Development

ADME Screening

Bioprocessing

Cell Based Assays

Chromatography

High Content Screening

High Throughput Screening

Imaging- Fluorescence / Microscopy

Mass Spectrometry

Next Generation Sequencing

PCR

Protein Purification / Crystallization

Solid-Phase Extraction

Clinical Diagnostics / Forensics Blood Analysis