Miniaturization of an Epigenetic HTRF® Assay with the Labcyte® Echo® Liquid Handler
12 March 2015

Epigenetics is emerging as an important target class for drug discovery and cancer research. As programs scale to evaluate new targets related to epigenetic expression, new tools are required to enable efficient high-throughput epigenetic screening. This poster shows the development of a methyltransferase assay in a 5 μL final volume with excellent results. It also demonstrates further miniaturization opportunities for screening and inhibitor characterization.