MALDI Imaging with Single Cell Resolution
23 Oct 2013
This application note, describes the feasibility of single cell imaging. Typically, high spatial resolution requires matrix preparation that is drier than usual and often is limited to high abundant lipid species.
For the high resolution imaging presented here, we utilized a dry sublimation device, which enabled us to perform MALDI imaging at a spatial resolution of 10μm and to resolve individual cells in tissue images.