Automated High-Density Sample Storage and Miniaturized Liquid Handling for High-Throughput Synthetic Biology Construct Assembly
30 July 2017

One of the main challenegs facing synthetic biology laboratories is the scaling up of workflows to meeting the growing demand for high-throughput construct assembly. This application note describes an automated, high-throughput workflow that has been integrated for the generation of synthetic DNA constructs at GeneMill, University of Liverpool, led by Dr James Johnson. It utilizes the TTP Labtech arktic® – an  automated, high-density -80°C sample storage and retrieval system – and TTP Labtech mosquito® single channel and multi-channel HTS liquid handlers. The workflow has increased productivity and standardization, as well as reducing turnaround time and cost at the GeneMill Facility.