Genome-wide association study on 13,167 individuals identifies regulators of blood CD34+ cell levels

Available on demand

Stem cell transplantation is crucial in the treatment of blood malignancies and requires the mobilization of CD34+ hematopoitic stem cells. Björn Nilsson, the Professor of Clinical Immunology at Lund University, Sweden, will present his research using the high throughput capabilities of Bio-Rad’s ZE5 Cell Analyzer, together with genome-wide association studies (GWAS) to better understand the genetic architecture of blood CD34+ cell levels as a means to identify potential targets for stem cell mobilization. This research was recently published in the prestigious journal Blood.

Key learning objectives

• How regulators of blood CD34+ cell levels can be identified
• How flow cytometry may be used in conjunction with GWAS for target identification
• The most significant regulators of CD34+ cell levels
• How PPM1H could be utilized as an inhibition target to facilitate stem cell harvesting by leukapheresis

Who should attend?

Researchers in Drug discovery, Drug screening and academia

Certificate of attendance

All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.