Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer by Thermo Fisher Scientific

Manufacturer Thermo Fisher Scientific  |   Model: IQLAAEGAAPFALGMBDK
4.4
/
5.0
  |  11 reviews
The Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometer combines high-performance quadrupole precursor selection with high-resolution, accurate-mass (HR/AM) Orbitrap™ detection.The superior quality of Q Exactive™ MS/MS data provides ultimate confidence for a wide range of qualitative and quantitative applications. Its high scan speed and spectral multiplexing capabilities make it fully compatible with UHPLC and fast chromatography techniques, ramping productivit... Read more


Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer by Thermo Fisher Scientific product image
Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer



Average Rating: 4.4
11 Scientists have reviewed this product

4 out of 5
Ease of use
4 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2019

  • Organization: Merck



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
Thermo Q Exactive Plus mass spectrometer is one of the best mass spectrometers.
Rating: 4.7

  • Application Area: Pharmaceutical analysis

"The Thermo Q Exactive Plus mass spectrometer is very powerful for unknown peak ID due to its high resolution and very good sensitivity. It greatly improved the work efficiency and shortened the time needed to complete an unknown peak ID."

Review date: 26 Mar 2019 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University Of Tennessee



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    3 out of 5
Easy to use
Rating: 3.7

  • Application Area:Metabolomics

"The PRM feature of the Q Exactive is really easy to use, and makes processing data simple"

Review date: 26 Mar 2019 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Hospira Health Care limited - A Pfizer company



  • Ease of use
    3 out of 5
    After sales service
    3 out of 5
    Value for money
    5 out of 5
Very good instrument. It is competing with TOF instrument.
Rating: 3.7

  • Application Area:Identification and charecterization

"Orbitrap helps to get Ultra High resolution mass of unknown components which helps to identify many unknown components."

Review date: 18 Feb 2019 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: CDPH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Best MS instrument. Highly recommended. 
Rating: 5.0

  • Application Area:Unknown screening, metabolism study, bioanalysis

"High resolution, high sensitivity, low noise, stable, easy care and operation, excellent tech service and support. Advanced software support with multiple functions and features data acquisition and analysis. "

Review date: 18 Feb 2019 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2014

  • Organization: Nestle research Center



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
It is a lab work-horse instrument, I will definitely miss it when it is not here.
Rating: 4.0

  • Application Area:Chemical analytics, lipid analytics

"The instrument is easy to use, very robust, it has good sensitivity and repeatability. The routine maintenance is very simple to follow. The after sales service is very good, the technical engineers are quite available for any problems and helpful."

Review date: 01 Nov 2018 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: university of Montreal



  • Ease of use
    4 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
Recommended for MS users.
Rating: 4.0

  • Application Area:Quantification and quatilication

"Very good product, robust, easy to use for quantification and qualification."

Review date: 05 Jul 2018 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2018

  • Organization: Faculte de Medecine



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Great instrument, I can't live without it!
Rating: 5.0

  • Application Area:Proteomic and Metabolomic

"Very confident in shotgun analysis and modifications of proteins. In Metabolomics, I am very confident in it's full scan analysis. The high resolution it offers enables good identifications of unknowns."

Review date: 16 Apr 2018 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: EMBL



  • Ease of use
    4 out of 5
    After sales service
    3 out of 5
    Value for money
    4 out of 5
The product is great in terms of HRMS
Rating: 3.7

  • Application Area:Metabolomics

"The product is great in terms of HRMS, robustness and ease to use. But the scan speed, sensitivity and data analysis resources are not perfect. HILIC are best alternative to normal phase for analyzing polar metabolites. But improvements in reproducibility and more life of column will add value to products."

Review date: 29 Jun 2016 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Advanced Reviewer

  • Member since: 2015

  • Organization: CDPH



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
As the great achievements with excellent data result, we very much favorite to this instrument.
Rating: 5.0

  • Application Area:Unknown compounds master screen

"1. This MS instrument has highest MS accuracy and very good MS resolution, and high sensitivity. 3. With high analytical reliability and reproducibility, we can achieve highest quality of MS identification data. 4. The instrument is very easy to be operated in both hardware and software. 5. The after-sale care, training (including on-site training), as well as instrument service is very satisfying, in both quickness/convenience and value of money. "

Review date: 27 Nov 2015 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Status:

    Reviewer

  • Member since: 2009

  • Organization: Biognosys AG



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 5.0
"The best mass spectrometer for the money. Good for shotgun analysis and excellent for data independent analysis."

Review date: 06 Oct 2015 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer


  • Status:

    Reviewer

  • Member since: 2013

  • Organization: GSK Vaccines



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
Rating: 4.7

  • Application Area:Biologics analysis

"It is as stable and robust as a 3Q, as accurate and selective as an Orbi, and as fast as required by best UPLCs. An incredibly productive instrument suitable for small molecules as well as for large-scale proteomics, polysaccharides as well as intact proteins (6000 Da mass range), and for qualitative works as well as targeted or label-free quantitation. All of this at an excellent level."

Review date: 22 Aug 2014 | Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer

The Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometer combines high-performance quadrupole precursor selection with high-resolution, accurate-mass (HR/AM) Orbitrap™ detection.

The superior quality of Q Exactive™ MS/MS data provides ultimate confidence for a wide range of qualitative and quantitative applications. Its high scan speed and spectral multiplexing capabilities make it fully compatible with UHPLC and fast chromatography techniques, ramping productivity to a new level. The Q Exactive instrument can easily handle routine applications in proteomics from bottom-up protein ID to semiquantitative isotopic labeling analyses to targeted quantification experiments.

The Q Exactive Plus Mass Spectrometer is superbly suited to untargeted or targeted screening with high-confidence confirmation, but is equally capable of a broad range of qualitative and quantitative applications. The superior quality of Q Exactive Plus Mass Spectrometer data enables characterization and quantitation of more compounds with greater confidence.


Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer Features:

  • Advanced quadrupole technology (AQT) improves precursor selection and transmission for more accurate quantitation of low-abundance analytes in complex matrices
  • Sophisticated data-independent acquisition (DIA) and parallel reaction monitoring (PRM) deliver reproducible quantitation with complete qualitative confidence
  • An advanced active beam guide (AABG) reduces noise and extends maintenance intervals
  • Optional intact protein mode allows greater control over collision pressure and related parameters for improved analysis of intact proteins and protein complexes
  • Optional enhanced resolution ensures maximum ID confidence in top-down proteomics and lipidomics