TaqBead™ Hot Start Polymerase by Promega Corp.

TaqBead™ Hot Start Polymerase(a) consists of spherical beads of wax containing Taq DNA polymerase. TaqBead™ Hot Start Polymerase facilitates hot-start PCR by keeping the enzyme sequestered in paraffin wax until the reaction temperature reaches approximately 60°C. This increases PCR specificity by keeping the polymerase separate from the rest of the reaction components until a critical temperature is reached, decreasing the probability of amplifying products that are the result of nonspecific binding of primers. The nonbarrier format of the bead is intended for use with heated-lid thermal cyclers or with the addition of a mineral oil overlay.