RNA Clean & Concentrator™-25 by Zymo Research

Manufacturer Zymo Research  |   Model: R1017
4.9
/
5.0
  |  15 reviews
The RNA Clean & Concentrator™-25 cleans and concentrates up-concentration at 10 µg of RNA in as little as 5 minutes.


RNA Clean & Concentrator™-25 by Zymo Research product image
RNA Clean & Concentrator-25
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Average Rating: 4.9
15 Scientists have reviewed this product

5 out of 5
Ease of use
5 out of 5
After sales service
5 out of 5
Value for money


  • Status:

    Reviewer
  • Member since: 2020

  • Organization: UCSD



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    5 out of 5
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Helpful kit for working with RNA.
Rating: 4.7

  • Application Area: Concentrate dilute RNA

"This kit has been very useful when I have an RNA sample that still has contamination in it after my normal extraction which happens sometimes. It is amazingly fast and easy. I have also used this in scenarios where my RNA is too dilute for an experiment and I need it more concentrated. Super easy."

Review date: 05 Jun 2020 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Iowa Hospitals and Clinics



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great kit - essential for RNA clean up.
Rating: 5.0

  • Application Area:RNA clean up for samples that are low concentration and/or contaminated with guanidinium.

"This kit is highly reproducible and reliable. Whenever I need to clean up samples and remove guanidinium contamination, I use this. Without it, some samples inhibit the reverse transcriptase enzyme, so they will not work in a downstream ddPCR assay. With the Zymo clean up kit, the guanidinium is removed and the RNA sample performs well in the assay."

Review date: 11 Dec 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of California, Los Angeles



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product, really lowered my background after clean up.
Rating: 5.0

  • Application Area:RNA clean up after RNA labeling

"This is a really nice kit for RNA cleanup. Just follow the manufacture protocol and it will help you get rid of all the small molecules after reaction. Highly recommended product."

Review date: 27 Nov 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: UCLA



  • Ease of use
    4 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Saved me time and did exactly what it was supposed to do.
Rating: 4.7

  • Application Area:Purify RNA

"The RNA Clean and Concentrator columns are well constructed and do exactly what they are supposed to do. I used them in my RT-PCR workflow and saved a lot of time. The only downside is that the volumes I had to use did not fit in the standard microcentrifuge tubes, so I had to split it into multiple and spin the liquid through the columns in more than one go. This is minor though and could potentially be avoided. Will continue using these for post-DNase treated RNA purification."

Review date: 27 Nov 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of the Sciences



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great results and quick, efficient kit.
Rating: 5.0

  • Application Area:Analyze RNA for sequencing

"The product is quick and easy to use with minimal steps but highly effective in purpose. I have been able to highly concentrate low-quantity samples by pooling together. I find it incredibly user-friendly too that I can go straight into using the kit using the aqueous phase of a trizol extraction."

Review date: 27 Nov 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of Delhi



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Good products, clean results.
Rating: 5.0

  • Application Area:Transcriptomics

"We use various products of Zymo for RNA work particularly. It gives clean results."

Review date: 07 Jun 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: University of California-San Francisco



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Essential part of the lab.
Rating: 5.0

  • Application Area:Next generation sequencing

"We use the RNA clean and concentrator kit to purify RNA for RNA-Seq. Its quick and easy to use, in 15-20 min you have your RNA ready to go! We don't have to wait too long for it once we have placed the order and support is always available if we need it. Although the kit is pretty straightforward so we rarely have issues with it."

Review date: 05 Jun 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Harvarv TH Chan School of Public Health



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great product but can be perfected.
Rating: 4.3

  • Application Area:RNA extraction

"Great product, easy to use, smart design of the columns, practical in-column DNase digestion. Now a couple of issues we have encountered: (i) sometimes the matrix of the column falls into pieces, or even goes through the columns, (ii) potentially related to the previous issue, we sometimes have a white precipitate in our purified RNA that is definitely not RNA, (iii) Zymo columns are only compatible with Zymo vacuum which itself is rather poorly designed with 20 slots (why not 24 like most centrifuge, etc?), unnecessary individual valve for each slot and the columns barely stand on the adapters."

Review date: 05 Jun 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: LMU München BMC



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Reliable kit, fast to use.
Rating: 5.0

  • Application Area:RNA clean up

"We have used this kit a lot in our lab for several years already. It always gives good results. RNA is clean, loss of RNA is in an accepatable range. Protocol is very fast."

Review date: 05 Jun 2019 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2019

  • Organization: Uniklinik Freiburg



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Superb results, essential to my work!
Rating: 5.0

  • Application Area:RNA-Protein interactions

"This kit is super easy to use and it saves me al lot of time while working. I've tested a couple of kits and with this one I get the highest yield amount of my RNA and the best quality, I wouldn't go back to any other brand. The delivery time after ordering is very good."

Review date: 05 Jun 2019 | RNA Clean & Concentrator™-25


  • Status:

    Reviewer

  • Member since: 2016

  • Organization: New York Genome Center



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great product, would recommend to others.
Rating: 5.0

  • Application Area:Footprinting and sample purification

"It was extremely easy to use and obtained good quality samples afterwards."

Review date: 29 Jul 2016 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Southern California



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Impressive and great results from this kit. Just like what ZYMO promised.
Rating: 5.0

  • Application Area:Human RNA clean up and concentration

"I got very high yields of RNA from this kit. Very impressive kit, easy to handle and quick processing step. I am very excited to get the high quality clean RNA by this kit."

Review date: 29 Jul 2016 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Cantabria University



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Easy to use, quickly and good results and good price
Rating: 5.0

  • Application Area:Basic research

"The effectiveness of the product is really good to get good quality RNAs. The results are reproducible and it is very easy to use. The rating of the product is a 5 over 5. And the price is not expensive."

Review date: 29 Jul 2016 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: University of Louisville



  • Ease of use
    5 out of 5
    After sales service
    5 out of 5
    Value for money
    5 out of 5
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Great result. Everybody should try this product.
Rating: 5.0

  • Application Area:For RNA isolation from the cells in culture and gene expression studies.

"I’ve never seen such purity of the RNA before. This product works excellent and easy to use and affordable."

Review date: 28 Jul 2016 | RNA Clean & Concentrator™-25
  • Status:

    Reviewer

  • Member since: 2016

  • Organization: Biofidal



  • Ease of use
    5 out of 5
    After sales service
    4 out of 5
    Value for money
    4 out of 5
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Great product!
Rating: 4.3

  • Application Area:RNA clean up before NGS

"The product is very easy to use, very quick protocol for an excellent RNA clean up. The product is also useful: it also purifies small RNA which is not the case of all RNA clean up columns "

Review date: 12 Jul 2016 | RNA Clean & Concentrator™-25

RNA Clean & Concentrator-25 provides a simple and reliable method for the rapid preparation of up to 50 µg of high-quality RT-PCR-ready RNA.  This simple procedure is based on the use of a unique single-buffer system and Zymo-Spin column technology that allows for selective recovery of total RNA (> 17 nt), large RNAs (> 200 nt), and/or small RNAs (17-200 nt).

The procedure is easy:  Add binding buffer and ethanol to your sample, then bind, wash and elute ultra pure RNA.  The RNA can be eluted from the Zymo-Spin IIC Column in as little as ≥25 µl of RNase-free water.  The highly-concentrated, purified RNA is suitable for all subsequent analyses and molecular manipulations.

The entire procedure typically takes about 5 minutes.