In conjunction with the PhysioMimix™ OOC Single, or Multi-Organ Microphysiological (MPS) Systems, MPS-T12 consumable plates are used to culture advanced 3D in vitro organ-a-chip models that provide fast, accurate and clinically translatable human data for improving the predictability of drug discovery.
The MPS-T12 consumable plate is designed for single organ-on-a-chip barrier model studies. It features 12 independent wells that are compatible with standard 24-well plate 0.33 cm2 Transwell® inserts.
MPS-T12 consumable plates provide novel insights into the effects of flow on organ cultures grown on Transwell® inserts, or simple dual-organ crosstalk studies within the same well. Dual-organ crosstalk studies are achieved by subjecting an organ tissue grown on the Transwell® to continual perfusion in the presence of a second tissue type that is cultured on an insert located at the base of the well. Example co-culture studies such as gut-liver, lung-liver, brain-liver or skin-liver assays.
Validated applications for MPS-T12 plates include:
MPS-T12 consumable plates are:
Contact CN Bio for more information about 3D in vitro models validated using MPS-T12 consumable plates, or guidance designing your own bespoke tissue or organ mimics.