Liquid-handling equipment can carry out simple and complex tasks, from filling plates to creating reagent mixes from multiple solutions. Standard liquid-handlers can perform these tasks, but their hardware is not designed to perform combinatorial dispensing patterns efficiently.
By applying a well-defined pressure pulse on top of the well a droplet is formed and a high precise and accurate nanoliter droplet is released into or onto nearly any destination. Larger volumes are achieved by applying up to 400 pulses per second. The “Immediate Drop on Demand Technology” (I-DOT) is a new approach for nano to microlitre liquid handling tasks.
It uses a patented noncontact pressure based dispensing technology. The general principle is simply based on a hole in the bottom of a microtiter plate well. Capillary forces keep the sample liquid in the cavity.
A new approach for complex liquid-handling tasks