Host cell proteins (HCPs) are contaminants found in biopharmaceuticals expressed in bacterial, yeast or mammalian production cell lines. Among protein expression cell lines, Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for industrial production of recombinant protein therapeutics. However, manufacturing and production processes of biopharmaceuticals often leave behind contaminating HCPs from CHO cells.
Pall ForteBio and Cygnus Technologies have jointly developed the Anti-CHO HCP Detection Kit for quantitation of residual HCPs. The Octet® platform's rapid high-throughput protein analysis combined with the broad HCP recognition and sensitivity of the industry-standard Cygnus 3G anti-CHO HCP antibody bring scientists the best of both worlds for HCP analysis.
- Unattended operation – Completely hands-off, walk-away HCP analysis
- Throughput – Fully analyzed HCP results for 96 samples in one hour
- High precision – Minimal assays variability in the range of 5-10% CV
- Sensitivity – Limits of detection as low as 0.5 ng/mL