Capto Core 400 is designed for intermediate purification and polishing of viruses and other large biomolecules.
Capto Core 400
Average Rating: 3.7
1 Scientist has reviewed this product
Status:
Reviewer
Member since: 2018
Organization: Adaptimmune Ltd
-
- Ease of use
- After sales service
- Value for money
Convenient and time-saving, has a wide enough range for different scale of operations.
Rating: 3.7
Application Area: Purification polishing step
"It works well in general and easy to use and the instructions are good."
Review date: 26 Jul 2018 | Capto Core 400
Novel core bead technology and multimodal ligand give Capto Core 400 dual functionality, size exclusion and binding chromatography, in one chromatography resin.
- Significantly improved productivity enabled by up to 100‑fold higher sample load and significantly higher flow rates compared with SEC.
- Bead with ligand‑activated core and inactive shell allows efficient capture of impurities, while target molecules are collected in the flowthrough.
- Straightforward optimization due to flow-through chromatography and robust performance, allowing for a wide window of operation.
Capto Core 400 is an excellent alternative to size‑exclusion chromatography (SEC) resins that are typically employed in the final stages of virus purification in vaccine manufacture.
