ARM-D Kit, MCR by Streck Inc.

Manufacturer Streck Inc.  |  Available Worldwide
The Streck ARM-D Kit, MCR is a multiplex real-time PCR kit for the rapid detection of antibiotic resistance genes in Gram-negative bacteria. This kit detects multiple variants the following plasmid-mediated mobilized colistin resistant (mcr) gene families: mcr-1, mcr-2 and mcr-3-4-5.


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ARM-D Kit, MCR
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The Streck ARM-D Kit, MCR is part of a family of comprehensive, multiplex real-time PCR kits that detect over 1,000 antimicrobial resistance (AMR) gene variants from 26 different gene target families. Streck ARM-D Kits provide a rapid detection strategy for monitoring β-lactam antibiotic resistance to improve AMR surveillance, aid in antibiotic stewardship programs and support infection control programs. The ARM-D MCR kit detects 48 variants in the following gene families: mcr-1, mcr-2 and mcr-3-4-5.

Streck ARM-D kits have a high degree of sensitivity and specificity for accurate, reliable results. Every kit includes positive controls for each target gene to monitor analytical process as well as an endogenous internal control (16SrRNA gene) to reduce false negatives due to PCR inhibition, DNA degradation or poor extraction.

The ARM-D MCR kit is an open-platform multiplex kit validated on the Applied Biosystems 7500 Fast and is compatible with most 4-channel real-time thermal cyclers. The kit allows for batch testing, increasing throughput for high volume testing and reducing cost per sample compared to cartridge-based methods.

Features

  • Detects and differentiates mcr-1, mcr-2 and mcr-3-4-5 gene families
  • Protocol can be completed in less than one hour
  • Compatible with most 4-channel real-time PCR thermal cyclers
  • Includes a premixed 2X master mix: DNA Polymerase, dNTPs, MgCl2 and reaction buffer
  • Includes positive controls for each gene target to monitor analytical process
  • Amplification protocol and analysis guides available

Benefits

  • Avoid false negatives; detect gene variants not covered by cartridge-based kits
  • Detect resistance mechanisms prior to obtaining susceptibility results
  • Batch testing reduces cost per sample compared to cartridge-based methods
  • Ensure accurate and reliable results with a high degree of sensitivity and specificity
  • Screen bacterial isolates for AMR genes to complement phenotypic testing
  • Improve surveillance, aid antibiotic stewardship programs and support infection control programs

For Research Use Only. Not for use in diagnostic procedures. A CE version of this kit is also available.