Mobile HomeCage enables neurophysiological experiments in freely-moving, non-anesthetized mice via a firm and stable head-fixation of an animal placed in a carbon-fiber enclosure suspended on a cushion of air.
Mobile HomeCage eliminates the need for anesthesia (and the biases that anesthetics introduce to the brain research), alleviates the stress experienced by animals under standard head-fixation conditions and enriches the experiment by exposing the animals to a variety of tactile, olfactory and visual stimuli. It allows combining two-photon / wide-field imaging, electrophysiology, optogenetics and electrochemistry with behavioral readouts.