Average Rating of 4.6/5.0

Based on 9 reviews

Trusted reviews provided by

Martina Chambers

STEMCELL Technologies

01 June 2020

5 review stars

Great instrument that has significantly improved our research capabilities!

We've had the Eclipse AF4 flow field flow fractionation system in our research and development lab for over a year now. The system itself is very easy to use, especially if you have a basic understanding of HPLC and/or SEC. We have been able to obtain successful separation of samples containing both digested and undigested antibodies, and isolation of nanoparticles from multiple supernatant components. Wyatt customer service is great - every time we have run into an issue, we have gotten a response from support in less than 24 hours and they have always been able to solve our problem. The instrument is very expensive, but it is highly versatile and has become a key piece of instrumentation in our lab.

Application Area: Characterization of antibodies, nanoparticles and extracellular vesicles

Paul Balding

Georgia Institute of Technology

27 May 2020

5 review stars

It is our view that the Wyatt Eclipse AF4 will replace GPC as the industry standard.

Field flow fractionation is a very difficult technique to master but the Wyatt Eclipse AF4 unit with included Scout predictive software, in addition to their 24/7 customer service, made method development and analyte characterization very achievable and enjoyable. Using one single instrument we have managed to separate and characterize polyelectrolytes with small radii from several nm up to hundreds of nm long rod like cellulose nanocrystals. The versatility and capability of this instrument is incredible and Wyatt's field reps must be credited for helping us realize the full potential of what AF4 can do.

Application Area: Molar mass, size and shape information for water soluble polymers, proteins and particles

Jacqueline Traber


27 May 2020

4 review stars

Wyatt Europe is the best partner for all service. Interesting webinars and exceptional customer service.

With Wyatt Europe, I have a really good partner in after sales and application development/method development. The system is very flexible and with the service contract I always can count on immediate remote-help. Although, I am not very happy with the dictated combination of hardware and software developments meaning that I am somewhat dependend on expensive software-changes for optimal use of the hardware, and respective bug-fixes. As a university research institute we don't have the money to change working hardware, like in industrial settings. Wyatt US only provides online help if the instrumentation is not older than 10years, which means the possibility to satisfy customers like us is only possible by making a lot of effort. The free webinars offered to us during COVID19 were more than helpful, including the user seminars in the last weeks.

Application Area: Analyzing NP-particle interactions with organic colloids in environmental systems

Marius Schmid

Zentriforce Pharma

17 April 2020

5 review stars

Nice and easy to use AF4 system.

Nice and easy to use AF4 system. For an AF4 system it is amazingly robust and can be applied to a wide range of applications. The option to use a frit-inlet channel is useful to test for focus stress induced changes of your material.

Application Area: ATMP, Peptides and Antibodies