Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, has announced the launch of two new chromatography media for process protein purification: CHT Ceramic Hydroxyapatite XT Media and Nuvia HP-Q Resin.
CHT Ceramic Hydroxyapatite XT (CHT XT) Mixed-Mode Media
CHT Ceramic Hydroxyapatite XT (CHT XT) Mixed-Mode Media was formulated in response to customers' need for a more robust and stable resin that can maintain the superior performance of CHT resins. CHT XT offers high resolution and efficient single-step clearance of aggregates and other impurities such as HCP, dsDNA, endotoxins, and leached Protein A. It can be used in applications such as purification of enzymes, monoclonal and polyclonal antibodies of various classes, antibody fragments, and bispecific antibodies; efficient isolation and purification of viruses and virus-like particles (VLPs); and, separation of supercoiled DNA from linear duplexes as well as single-stranded from double-stranded DNA.
Key benefits of CHT XT Media
Nuvia HP-Q Anion Exchange Resin
Nuvia HP-Q Anion Exchange Resin was introduced to fill customers’ need for a high-performance resin compatible with high-throughput (HTP) large biomolecule purification. It can be used for downstream purification of large molecules such as high molecular weight (HMW) plasma proteins IgA and IgM, viruses, VLPs, and PEGylated proteins.
Key benefits of Nuvia HP-Q Resin
Both media will be on display at BioProcess International Conference & Exhibition in Boston, September 5–7. At the event Bio-Rad will also host daily Design of Experiment (DoE) Workshops in Booth 1617 to discuss best strategies for screening new resins and tools to facilitate experimental design. Highlights of DoE workshop include: