Accelerating Science: How to cure the incurable with cell and gene therapy

Cell Line Development



Monitoring product quality attributes (PQAs) throughout monoclonal antibody (mAb) development is vital to ensuring drug safety and efficacy. During the manufacturing process, heterogeneity can occur due to enzymatic cleavage and chemical posttranslational modifications (PTMs). In addition, process changes can happen during manufacturing which can result in PTMs that impact product quali...