Cell & Gene Therapy



CRISPR-generated CAR T-cells: A new frontier in the treatment of solid tumors

CAR T-cell therapy is a revolutionary treatment for cancer that uses genetically modified immune cells to selectively kill cancerous cells in the body. The first FDA-approved CAR T-cell therapy was released in 2017 for acute B-cell lymphoblastic leukemia, and since then, several other CAR T-cell therapies have been developed and have achieved remarkable remission rates against a range o...

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Designing CAR-T cell therapy for clear cell renal cell carcinoma: preclinical evaluation using cell sorting and single cell sequencing

Chimeric antigen receptor (CAR)-T cell therapy is a new type of “living drug” that has...

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